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Combinatorial Drug Discovery Program (CDDP) and the High-throughput Flow Cytometry Program (HtFCP)

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Houston

Contact:
Clifford Stephan, PhD
Associate Professor, Department of Translational Medical Sciences, Texas A&M Health Institute of Biosciences and Technology

Email: cstephan@tamu.edu

Phone: (713) 677-7456

Visit Website

Website: https://ibt.tamu.edu/index.html

The Texas A&M Combinatorial Drug Discovery Program (CDDP) and High Throughput Flow Cytometry Program (HtFCP) are components of the Gulf Coast Consortia network of drug discovery core facilities offering to academic and commercial users access to state of the art in high throughput biochemical and phenotypic screening services for single agent and combinatorial drug discovery research. The program has specialized capabilities for supporting small molecule and biologics screening in a range of in vitro model systems including 2D monolayers, 3D organoids, other ex vivo patient-derived cells, as well as radio-sensitizer screens. The CDDPs screening platforms include fully automated high throughput confocal and metabolic imaging, high-throughput flow cytometry, and multi-modal biochemical endpoint detection systems. Data analysis services include both traditional statistical methods and advanced machine learning/AI technologies to contextualize pharmacologic, genomic, and transcriptomic interactions.